“New Sepsis Guidelines Released!” from PulmCCM

Substack – PulmCCM

The following preview and article are from PulmCCM, “an information service for critical care professionals.” You can register on their websitewww.pulmccm.org, to access their Substack, which features hundreds of useful articles.

Here is an excerpt from their article, New Sepsis Guidelines Released!

With more than 5,400 studies on sepsis published in the past five years, though, surely there have been important recent discoveries ready for dissemination from the halls of academia to bedside clinical care in the community?

The Surviving Sepsis Campaign is the premier group that has tasked itself with periodically wrangling this expanding corpus of errant and unruly information into a set of statements that convey an impression of continuous evidence-based progress in sepsis care. Since the Campaign’s inception in 2001, its panelists have regularly analyzed sepsis research and issued recommendations governing multiple aspects of care, whose authority is undiminished by a lack of strong supporting evidence.

The most recent tranche of guidelines, issued in March 2026, includes “129 statements, with 46 being new statements not previously addressed, and more definitive recommendations” than the 2021 iteration.

We’ll put these under the microscope in future posts, but here are a few of the major takeaways from the new guidance. (Read the full article on the Substack).

PulmCCM is not affiliated with the Surviving Sepsis Campaign or any specialty society.